The Australian Bone Marrow Donor Registry is a register of people willing to donate bone marrow or blood stem cells to give a transplant patient a second chance at life. ABMDR is linked to a worldwide network of donor registries which can be searched for those patients. The decision to become a marrow/ blood stem cell donor requires careful consideration and we hope that this information will assist you in making an informed decision.


Each year thousands of people are diagnosed with leukaemia or other life threatening blood disorders. A bone marrow/ blood stem cell transplant is the only possible treatment for many of these people to save their lives.

Searching the same ethnic group as the patient greatly increases the chance of finding a match, so your ethnic background is important. Please indicate your family background on the enrolment form at registration (for example Southern European or Northern Chinese).


Governments only fund the registration of blood donors who want to join ABMDR’s registry. When a blood donor requests to join the registry, they will provide an additional blood sample to allow ABMDR to identify their tissue type and blood type, as well as screen for a particular virus relevant to transplantation (cytomegalovirus or CMV).

You will also need to complete the donor enrolment form that will confirm your eligibility to join. Although ABMDR has fewer restrictions compared to blood donation, as only blood donors are currently able to join the registry, you will need to meet the Australian Red Cross Lifeblood’s eligibility criteria.

The enrolment form will also ask whether you would like your health data to be used for ethically approved research projects.


Australian governments only fund the Australian Red Cross Lifeblood to recruit donors onto ABMDR’s registry. Unfortunately, ABMDR is not funded to recruit donors directly.

ABMDR is committed to establishing an easy pathway for non-blood donors to join the registry, and increasing Australia’s low donor recruitment numbers. In 2019, ABMDR launched the ‘Strength to Give’ campaign, as a demonstration of how easy recruiting donors online using cheek-swabs is – and why this method is used by all other international registries. This campaign is currently paused while we await government support.


It is natural to want to help a friend who needs a marrow/blood stem cell transplant, but unfortunately you are almost certainly not going to be a match for their tissue type. ABMDR will search the world to find a match for your friend.  However, if you join the registry, you may be found to help save the life of any person in need of a transplant.


Your tissue type is entered into ABMDR’s registry, which is then linked  to the worldwide registries. When a patient needs a donor, their tissue type is compared with all potential donors on the registries worldwide. If you then match with a patient you will be contacted by ABMDR and asked to confirm your commitment to be a donor and provide blood sample to confirm this match. In Australia, only 1 in 1,500 donors will be asked to donate stem cells in any year.

Your health and wellbeing before and after donation are very important to us. If you are chosen to become a donor, an independent specialist with detailed knowledge of stem cell donation will assess you medically and answer any questions you may have. In Australia, donation occurs in one of the major hospitals in the state capital cities. You would not be required to travel interstate or overseas.


Joining the donor pool is voluntary and you may withdraw at any time. Deciding to donate your stem cells is an important decision. There are many reasons why you may decline, such as poor health, the time involved or concern about the risks. There is however a ‘point of no return’ for the patient. About a week before the actual donation, the patient’s own bone marrow is destroyed in preparation for receiving the donated stem cells. At this point the patient will die unless healthy bone marrow is transplanted. It is therefore very important that you let us know well before this ‘point of no return’ if you have any concerns regarding donation.


There are two ways you can donate your bone marrow/blood stem cells. The actual donation method best for you will be assessed by a medical specialist prior to your blood stem cell donation but ultimately you will be able to choose the method of collection.

1. Peripheral blood stem cell donation

Normally the number of stem cells circulating in the blood is low. To increase the number of blood stem cells, a hormone-like substance called Granulocyte Colony Stimulating Factor (G-CSF) is injected under the skin daily for 4 days prior to the collection. The stem cells are then collected by a procedure called leukapheresis. During this procedure a needle is inserted into a vein in your arm and your blood passes into a cell separator machine, which selectively removes the stem cells.
The remaining blood components are immediately returned to your body. This procedure is performed at a hospital or blood donor centre, does not require a general anaesthetic and takes approximately 3 to 4 hours. After the procedure you may leave but another donation the following day may be necessary if not enough cells are collected.

What are the risks?

G-CSF is usually well tolerated, although during the course of the injections, you may have bone pain and some flu-like symptoms, which usually respond to paracetamol.

G-CSF is also used to treat patients. As yet no significant long term side effects have been observed with prolonged administration of G-CSF to patients, but the long term effects of short treatments in donors is unknown. There have been some rare side effects which have been reported and these will be discussed in more detail if you match a recipient.

2. Bone marrow donation

Blood stem cells found in the bone marrow can be collected under general anaesthetic. Using a needle and syringe, the marrow is extracted from the pelvic bone cavity. This procedure can take up to two hours. In the month before the collection you may be asked to donate one or two units of blood. This blood is stored and may be returned to you after the collection.

The time needed for complete recovery varies, but generally you can go home the same or next day, and resume your normal activities after two or three days. Normal bone marrow will re-grow rapidly to replace the collected bone marrow.

What are the risks?

The risks for donating stem cells by this method are the same as those with any procedure involving a general anaesthetic. The chance of a serious complication is very low.

Some people may experience nausea and/or local pain and discomfort for several days.


About a week before the transplant, the patient has chemotherapy and/or radiotherapy to destroy their diseased bone marrow. They receive the healthy donated stem cells in a similar way to a blood transfusion.


We just ask you give some of your time.  ABMDR will cover all medical and hospital expenses related to the stem cell donation. Incidental expenses associated with donation such as travel to and from hospital and accommodation if necessary, will be paid for. Donating stem cells is voluntary and you will not receive any payment.


You may be asked to donate stem cells on a second occasion for the same patient if the first transplant did not ‘take’, or if the patient’s condition changes. Other types of blood products may also be requested for that patient such as a normal blood donation or white blood cell donation which is collected by a cell separator machine. It is highly unlikely that you would be asked to donate to more than one recipient needing a transplant, although it has happened.

If you donate to a patient, you will be removed from the Registry’s active list for two years. This means that no patient other than the one you donated to can match with you in this time. The patient you donated to may still need additional cell products from you, depending on how their transplant progresses.

At the end of the two years, you will automatically be re-activated for all patients. Around this time, a donor coordinator will contact you and discuss whether you wish to remain on the registry.


Your details are treated confidentially. Please refer to the ABMDR Privacy Policy for more information.


You may receive progress reports on the patient after transplant. Donors and patients are not encouraged to meet, although if both parties agree and provide written consent, contact can be made.


Following chemotherapy or stem cell transplantation patients often develop very low platelet counts. Platelets are needed to control bleeding. You may be able to become a platelet donor. For more information visit donateblood.com.au


Please remember to tell us of:

  • changes in your contact address and telephone numbers
  • changes in your personal details e.g. last name changes
  • changes in your health that may prevent you from donating
  • permanently or temporarily, including pregnancy
  • changes in your commitment to remain on the Registry.

You can find this information in other languages in the Donor Brochures page in this website.